The good thing about a flight simulator is that it requires very little maintenance. Nevertheless, you should clean it regularly. But you know how it is: you often procrastinate, even though it doesn't take long at all. ;-)
A cloth will quickly prove ineffective due to the many buttons and switches. The easiest way is to use a vacuum cleaner with a suitable attachment. Windows and controls are best cleaned with mild soapy water. This is also perfectly adequate for disinfection.
Warning! Avoid harsh cleaning agents, such as chlorine-based disinfectants. You should also refrain from using glass cleaners on panels and flight controls, as this may cause the paint to peel off over time.
Happy clean flying!